Xylaria nigripes, also known as O Linh ginseng, is a medicinal herb used in traditional medicine for its sedative effects, treatment of insomnia, and blood pressure reduction. It is especially beneficial for people recovering from surgery, childbirth, or breastfeeding, and is believed to improve memory, protect the brain, and nourish the kidneys.

According to research, XN, a fungus from the Xylariaceae family, exhibits various bioactivities, including antioxidant, immunomodulatory, anti-inflammatory, and neuroprotective effects. It has shown potential in enhancing insulin sensitivity and preventing spatial memory impairment. Studies using hydrogen peroxide-induced oxidative stress models in neural cells suggest that XN extracts can protect against oxidative damage and mitochondrial dysfunction.

These benefits are attributed to compounds like polysaccharides, adenosine, polyphenols, and triterpenoids found in XN mycelia.