This satisfying casserole delivers all the bold flavors of the Wild West—no open flame required. Inspired by the iconic cowboy actor, John Wayne Casserole is a hearty, layered dish that has become a beloved comfort food favorite.
With seasoned beef, spicy accents, a creamy layer, and a biscuit crust, it’s a go-to for feeding a hungry crowd or making weeknight dinners extra cozy.
What Is John Wayne Casserole?
It’s a warm, oven-baked dish built in layers—starting with a soft biscuit base, topped with taco-seasoned ground beef, diced tomatoes with green chilies, and onions. That’s followed by a creamy mixture of sour cream, mayo, and cheddar cheese, then finished with more melty cheese on top. This dish is a hit at potlucks, family dinners, or anytime comfort food is calling.